Colony stimulating Factors Active on Human Bone Marrow Cells
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چکیده
Colony-stimulating factors (CSF) active on five subgroups with different capacities to both human and murine bone marrow stimulate mouse granulocyte and macrocolony-forming units in culture (CFU-C) phage progenitors. CSF in these five peaks were found in the conditioned medium of were eluted from an Ultrogel AcA 44 gel Yoshida sarcoma cells (line YSSF-212T), filtration column withapparent molecular although the cells originated from rats. weights of 22,000-25,000 daltons. CSF of The CSF were inactivated by digestion nonhuman origin stimulating human with trypsin, a-chymotrypsin, and CFU-C would be useful in hematologic pronase. By chromatography on DEAEstudies of bone marrow cells. cellulose, the CSF were separated into
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تاریخ انتشار 2005